Sperm Nuclear Maturation - A Basic & Clinical Approach (Paperback)

In somatic cells, DNA is normally wrapped around the histones octamer to forms nucleosomes that eventually give rise to a solenoid DNA structure. Unlike somatic cells, in mammalian sperm, the development of spermatids into mature spermatozoa is accomplished by a series of structural and chemical modifications including a gradual replacement of lysine-rich histones by transition proteins and then by protamines which bind more tightly to DNA than histones, which results in compaction of chromatin in the sperm nucleus, a process which is termed 'sperm chromatin condensation'. This book examines the several techniques that have been devised in order to study chromatin and DNA defects in human spermatozoa.

General

Imprint:	nova science publishers
Country of origin:	United States
Release date:	October 2011
First published:	March 2011
Authors:	Ali Reza Talebi
Dimensions:	155 x 230 x 9mm (L x W x T)
Format:	Paperback
Pages:	129
ISBN-13:	978-1-61668-194-4
Categories:	Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > DNA
LSN:	1-61668-194-2
Barcode:	9781616681944

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