Brucella is a genus of Gram-negative, facultative, intracellular
bacteria that are highly pathogenic for a variety of mammals,
including humans. Recently the WHO cited brucellosis to be the
world's most widespread zoonosis. An important feature of the
pathogenicity of these organisms is their ability to survive and
replicate within the host macrophages. However the mechanism for
this is unclear. In addition, none of the classical bacterial
virulence factors found in other bacterial pathogens have been
found in the genomes of the forty Brucella species and biovars
analysed to date. Nevertheless the application of systems biology
approaches in recent years has transformed research, permitting
fascinating new insights into Brucella molecular biology and
genomics. Written by highly acclaimed Brucella scientists, this
book comprehensively reviews the most important advances in the
field. Opening chapters focus on genetic diversity within Brucella,
covering both classical and new species. Pa
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