This volume will bring together a review of research being carried
out by international experts in this field, detailing treatment and
research approaches in several forms of malignant brain tumors.
These include glioblastoma (GBM), a highly aggressive and fatal
form of astrocytoma which accounts for 80% of newly diagnosed brain
tumor patients per year, and meningioma, of which 10% are malignant
and extremely resistant to targeted therapies. The volume will also
include a discussion of methods to overcome blood-brain barrier
exclusion for more efficient targeted drug delivery in all forms of
brain cancer treatment. The volume will include information on the
repurposing of drugs in an attempt to circumvent drug resistance,
use of small molecule inhibitors in GBM treatment, mechanisms of
secondary brain metastasis, drug resistance, and state-of-the-art
imaging of targeted therapies.
General
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