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Molecular Genetics of Axial Patterning, Growth and Disease in the Drosophila Eye (Paperback, Softcover reprint of the original 1st ed. 2013)
Loot Price: R5,278
Discovery Miles 52 780
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Molecular Genetics of Axial Patterning, Growth and Disease in the Drosophila Eye (Paperback, Softcover reprint of the original 1st ed. 2013)
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Undoubtedly, Drosophila melanogaster, fruit fly, has proved to be
one of the most popular invertebrate model organisms, and the work
horse for modern day biologists. Drosophila, a highly versatile
model with a genetic legacy of more than a century, provides
powerful genetic, cellular, biochemical and molecular biology tools
to address many questions extending from basic biology to human
diseases. One of the most important questions in biology focuses on
how does a multi-cellular organism develop from a single-celled
embryo. The discovery of the genes responsible for pattern
formation has helped refine this question, and led to other
questions, such as the role of various genetics and cell biological
pathways in regulating the crucial process of pattern formation and
growth during organogenesis. Drosophila eye model has been
extensively used to study molecular genetic mechanisms involved in
patterning and growth. Since the genetic machinery involved in the
Drosophila eye is similar to humans, it has been used to model
human diseases and homology to eyes in other taxa. This book will
discuss molecular genetic mechanisms of pattern formation,
mutations in axial patterning, Genetic regulation of growth in
Drosophila eye, and more. There have been no titles in the past ten
years covering this topic, thus an update is urgently needed.
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