Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases
elucidates elaborately the role of caspase enzymes implicated in
the initiation of molecular events leading to neuronal apoptosis in
the neurodegenerative disease. The book starts with introduction to
neuropathology, neurogenetics, and epidemiology of
neurodegenerative disease and illustrates the involvement of human
caspases, neuronal apoptosis, apoptotic pathways, genetic
polymorphisms, and several other factors and underlying mechanisms
in the pathology of Alzheimer's disease, Parkinson's disease, and
Huntington's disease. An important focus in all chapters is the
intricate mechanisms and interplay that occur during or leading to
neuron death in neurodegenerative diseases, along with disease
pathobiology.
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