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Synthesizing Hope - Matter, Knowledge, and Place in South African Drug Discovery (Paperback)
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Synthesizing Hope - Matter, Knowledge, and Place in South African Drug Discovery (Paperback)
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Synthesizing Hope opens up the material and social world of
pharmaceuticals by focusing on an unexpected place: iThemba
Pharmaceuticals. Founded in 2009 with a name taken from the Zulu
word for hope, the small South African startup with an elite
international scientific board was tasked with drug discovery for
tuberculosis, HIV, and malaria. Anne Pollock uses this company as
an entry point for exploring how the location of the scientific
knowledge production matters, not only for the raw materials,
production, licensing, and distribution of pharmaceuticals but also
for the making of basic scientific knowledge. Consideration of this
case exposes the limitations of global health frameworks that
implicitly posit rich countries as the only sites of knowledge
production. Analysis of iThemba identifies the problems inherent in
global north/south divides at the same time as it highlights what
is at stake in who makes knowledge and where. It also provides a
concrete example for consideration of the contexts and practices of
postcolonial science, its constraints, and its promise.
Synthesizing Hope explores the many legacies that create conditions
of possibility for South African drug discovery, especially the
specific form of settler colonialism characterized by apartheid and
resource extraction. Paying attention to the infrastructures and
laboratory processes of drug discovery underscores the materiality
of pharmaceuticals from the perspective of their makers, and
tracing the intellectual and material infrastructures of South
African drug discovery contributes new insights about larger
social, political, and economic orders.
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