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Long Non-coding RNA - The Dark Side of the Genome (Hardcover) Loot Price: R3,039
Discovery Miles 30 390
You Save: R209 (6%)
Long Non-coding RNA - The Dark Side of the Genome (Hardcover): Antonin Morillon

Long Non-coding RNA - The Dark Side of the Genome (Hardcover)

Antonin Morillon

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List price R3,248 Loot Price R3,039 Discovery Miles 30 390 | Repayment Terms: R285 pm x 12* You Save R209 (6%)

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The dark side of the genome represents vast domains of the genome that are not encoding for proteins - the basic bricks of cellular structure and metabolism. Up to 98% of the human genome is non-coding and produces so-called long non-coding RNA. Some of these non-coding RNA play fundamental roles in cellular identity, cell development and cancer progression. They are now widely studied in many organisms to understand their function. This book reviews this expanding field of research and present the broad functional diversities of those molecules and their putative fundamental and therapeutic roles and develops the recent history of non-coding RNA, their very much debated classification and how they raise a formidable interest for developmental and tumorigenesis biology. Using classical examples and an extensive bibliography, the book illustrates the most studied and attractive examples of these long non-coding RNA, how they interface with epigenetics, genome integrity and expression and what are the current models of their regulatory mechanisms.

General

Imprint: ISTE Press Ltd - Elsevier Inc
Country of origin: United Kingdom
Release date: February 2018
First published: 2018
Authors: Antonin Morillon
Dimensions: 229 x 152 x 15mm (L x W x T)
Format: Hardcover
Pages: 190
ISBN-13: 978-1-78548-265-6
Categories: Books > Science & Mathematics > Biology, life sciences > Molecular biology
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LSN: 1-78548-265-3
Barcode: 9781785482656

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