Leading clinicians and investigators review in a comprehensible and
user-friendly style all the latest information about the molecular
biology of cell cycle control and demonstrate its clinical
relevance to understanding neoplastic diseases. Topics range from
Cdk inhibitors and cell cycle regulators to the prognostic value of
p27 and tumor suppressor genes as diagnostic tools. Actual case
studies show how the new molecular understanding has produced such
drugs as Flavopiridol and Sulindac. The book brings all the recent
critical research findings to bear on clinical practice, and
clearly shows their powerful impact on the diagnostics,
prognostics, and therapeutics of cancer, AIDS, and cardiovascular
disease.
General
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