Excessive growth of cyanobacteria leads to blooms. These blooms
severely affect the aquatic ecosystem. This work describes the
utilization of these bloom forming Cyanobacteria as potential
sources of antibacterial agents. Antibacterial activity is the
antagonistic effect exerted by the microbes on other living
species. Cyanobacteria have a tendency to produce secondary
metabolites which prevent the growth of bacteria.The antibacterial
property of these microbes is due to their excellent acumen to
produce secondary metabolites which prevent the growth of bacteria.
The inhibition of the bacterial growth is by interfering with the
protein synthesis, retarding the metabolism and rupturing the cell
wall of bacteria. In this study, we have explored the antibacterial
potential of two bloom forming cyanobacteria Anabaena variabilis
and Synechococcus elongates against clinically isolated human
pathogenic gram negative bacteria Escherichia coli, Enterococcus
sp., Klebsiella sp. Exploring Cyanobacteria for antibacterial
property can help us in their application as antimicrobial drug and
thus prevent the various problems related to drug resistance and
side effects of present day drugs.
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