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Lethal Decisions - The Unnecessary Deaths of Women and Children from HIV/AIDS (Hardcover)
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Lethal Decisions - The Unnecessary Deaths of Women and Children from HIV/AIDS (Hardcover)
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This first-person account by one of the pioneers of HIV/AIDS
research chronicles the interaction among the pediatric HIV/AIDS
community, regulatory bodies, governments, and activists over more
than three decades. After the discovery of AIDS in a handful of
infants in 1981, the next fifteen years showed remarkable
scientific progress in prevention and treatment, although blood
banks, drug companies, and bureaucrats were often slow to act. 1996
was a watershed year when scientific and clinical HIV experts
called for treating all HIV-infected individuals with potent triple
combinations of antiretroviral drugs that had been proven
effective. Aggressive implementation of prevention and treatment in
the United States led to marked declines in the number of
HIV-related deaths, fewer new infections and hospital visits, and
fewer than one hundred infants born infected each year.
Inexplicably, the World Health Organization recommended withholding
treatment for the majority of HIV-infected individuals in poor
countries, and clinical researchers embarked on studies to evaluate
inferior treatment approaches even while the pandemic continued to
claim the lives of millions of women and children. Why did it take
an additional twenty years for international health organizations
to recommend the treatment and prevention measures that had had
such a profound impact on the pandemic in wealthy countries? The
surprising answers are likely to be debated by medical historians
and ethicists. At last, in 2015, came a universal call for treating
all HIV-infected individuals with triple-combination antiretroviral
drugs. But this can only be accomplished if the mistakes of the
past are rectified. The book ends with recommendations on how the
pediatric HIV/AIDS epidemic can finally be brought to an end.
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