In 1996 the 75th anniversary of the discovery of insulin was
celebrated at the University of Toronto, the scene of that
discovery in 1921. This volume was stimulated by the scientific
program which was staged at that time and brought together much of
the world's best talent to discuss and analyze the most recent
developments in our understanding of pancreatic function, insulin
secretion, the interaction of insulin with its target tissues, the
mechanism of insulin action at the cellular level, and the defects
which underlie both Type I (insulin-dependent diabetes mellitus,
IDDM) and Type II (noninsulin-dependent diabetes mellitus, NIDDM)
forms of the disease. We have chosen to focus the present volume on
work related to insulin action.
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