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Myelodysplastic Syndromes & Secondary Acute Myelogenous Leukemia - Directions for the New Millennium (Hardcover, 2001 ed.)
Loot Price: R4,323
Discovery Miles 43 230
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Myelodysplastic Syndromes & Secondary Acute Myelogenous Leukemia - Directions for the New Millennium (Hardcover, 2001 ed.)
Series: Cancer Treatment and Research, 108
Expected to ship within 12 - 17 working days
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Myelodysplastic syndromes are to the bone marrow what pneumonia is
to the lungs; the response of an organ to a variety of etiologic
insults like aging, toxic exposure, infections and auto-immunity.
Among infectious causes alone, pneumonia could be the result of a
variety of possible pathogens including bacterial, viral,
tuberculous or fungal agents. Similarly, MDS cannot be treated as a
single disease. Attempts to harness the inherent complexity of MDS
by devising classifications' which group the various syndromes as
one disease is as misguided as saying that a pneumonia is not
infectious because it did not respond to antibiotics. Progress in
the field will occur faster when we re-analyze this premise.
Therefore, until a clearer picture of the disease emerges it is
best to treat each of the MDS syndromes as a separate entity.
Having no classification is better than a misleading one. Cancer
research has been notable for its periodic cycles of promise and
hope, followed by defeat and disappointments. It is not that there
is no solution, but that the problem has not been identified
precisely. This book is our attempt to define the most crucial
questions related to MDS that need to be addressed immediately
through logic, analysis and rigorous experimentation. If the
emerging problems appear daunting, then instead of being
overwhelmed by them, we should follow the advice of the great 20th
century thinker Antonio Gramsci, pessimism of the intellect must be
faced with the optimism of will'.
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