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Fetal Islet Transplantation (Paperback, Softcover reprint of the original 1st ed. 1995)
Loot Price: R1,458
Discovery Miles 14 580
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Fetal Islet Transplantation (Paperback, Softcover reprint of the original 1st ed. 1995)
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Despite the advent of insulin for clinical use in 1922, our ability
to control hypergly cemia and prevent the long term sequelae ofthe
disease remains limited. Thus normalization of the milieu interieur
with physiologic responses of insulin and metabolites remains an
elusive but critically important goal. The developing endocrine
pancreas provides a model system that speaks to many challenges of
the transplantation biologist. Thus the attempt to of
vascularization, growth and development, immunologic toler
recapitulate the ontogeny ance, and glucose responsive insulin
secretory capacity of fetal islet tissue provides a tantalizing
possibility to replace insulin secreting tissue in persons with
diabetes. Studies of this tissue are also important because of the
implications such investigations have for genetic and molecular
biological approaches to restoring insulin secretion as well as for
providing clues to enhancing the growth and repair of islets that
have been the target of autoimmune disease. Investigators in the
area offetal islet transplantation comprise a small group scattered
throughout the world scientific community. Therefore it seemed
important to provide a forum where these scientists could gather,
share ideas, and achieve consensus such that progress in this
rapidly evolving area could be facilitated. The conference would
have remained a dream if the support of the Okla Basil Meade, Jr.
family had not made it manifest."
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