The past 25 years has seen the emergence of a wealth of data
suggesting that novel biological functions of known proteins play
important roles in biology and medicine. This ability of proteins
to exhibit more than one unique biological activity is known as
protein moonlighting. Moonlighting proteins can exhibit novel
biological functions, thus extending the function of the proteome,
and are also implicated in the pathology of a growing number of
idiopathic and infectious diseases. This book, written by a cell
biologist, protein evolutionary biologist and protein
bioinformatician, brings together the latest information on the
structure, evolution and biological function of the growing numbers
of moonlighting proteins that have been identified, and their roles
in human health and disease. This information is revealing the
enormous importance protein moonlighting plays in the maintenance
of human health and in the induction of disease pathology. Protein
Moonlighting in Biology and Medicine will be of interest to a
general readership in the biological and biomedical research
community.
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