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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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DNA and RNA Cleavers and Chemotherapy of Cancer and Viral Diseases (Paperback, Softcover reprint of the original 1st ed. 1996)
Loot Price: R1,636
Discovery Miles 16 360
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DNA and RNA Cleavers and Chemotherapy of Cancer and Viral Diseases (Paperback, Softcover reprint of the original 1st ed. 1996)
Series: NATO Science Series C, 479
Expected to ship within 10 - 15 working days
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The past decade has witnessed a burst of activity and interest in
the discovery and design of drugs that cleave DNA and RNA with
sequence specificity. This interest stems from the potential of
this class of compounds to be useful as therapeutics agents, in
particular in the field of the treatment of cancer and viral
diseases. Further, a side benefit of such studies is the discovery
of novel mechanisms and uses of such agents as tools in the study
of structure and function of nucleic acids. Up to now, no
international meeting has been organized to recognize the immense
progress that has been made in this field. The field of DNA and RNA
cleavage by natural and chemical drugs now includes researchers
working with rather dissimilar agents but with common underlying
mechanisms of DNA damage. Until recently, these scientists were
working in separate, apparently unrelated areas, such as the
enediyne antibiotics and their synthetic analogues, bleomycin-metal
complexes, metal-drug complexes, ribozymes and ribozyme mimics, and
antisense and antigene oligonucleotides, etc. It is now clear that
these research areas have in common strategies and targets.
Researchers representing these areas worked together at this
workshop where these common interests were discussed and scientific
ideas modified and criticized. Such a workshop should lead to new
research approaches and collaborative interactions, and is expected
to significantly enhance the progress in the field of DNA and RNA
cleavage.
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