Computational Design of Ligand Binding Proteins (Paperback, Softcover reprint of the original 1st ed. 2016)

This volume provides a collection of protocols and approaches for the creation of novel ligand binding proteins, compiled and described by many of today's leaders in the field of protein engineering. Chapters focus on modeling protein ligand binding sites, accurate modeling of protein-ligand conformational sampling, scoring of individual docked solutions, structure-based design program such as ROSETTA, protein engineering, and additional methodological approaches. Examples of applications include the design of metal-binding proteins and light-induced ligand binding proteins, the creation of binding proteins that also display catalytic activity, and the binding of larger peptide, protein, DNA and RNA ligands. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Molecular Biology, 1414
Release date:	April 2018
First published:	2016
Editors:	Barry L. Stoddard
Dimensions:	254 x 178 x 21mm (L x W x T)
Format:	Paperback
Pages:	375
Edition:	Softcover reprint of the original 1st ed. 2016
ISBN-13:	978-1-4939-8080-2
Categories:	Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
LSN:	1-4939-8080-7
Barcode:	9781493980802

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