Following remarkable advances in medical care. the past decade has
witnessed a significant improvement in the survival of patients
with many different forms of heart disease. In the majority
ofcases. however. the advances have been pa lIiative and not
curative. The resu It has been the prod uction of an
ever-increasing population of patients with heart disease. many of
whom suffer from myocardial dysfunction and latent or overt heart
failure. Heart failure is now a major cause of morbidity and
mortality in cardiac patients. This book aims to combine in a
single volume data relating to both pathophysiological mechanisms
and the clinical management of the patient with heart failure. It
includes chapters dealing with molecular. biochemical. and
pathophysiological aspects of heart failure. ven tricular function
and its assessment. and the clinical aspects of heart failure in
different cardiac disorders, including ischemic heart disease.
valvular heart disease. and the cardiomyopathies. There are
sections on pharmacotherapy. the role of arrhythmias, exercise
physiology. and neurohumoral mechanisms. The book also deals with
newer inter ventional techniques. newer surgical procedures and
some current problems relating to cardiac assist devices and heart
and heart-lungs transplantation."
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