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Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
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Proteinases as Drug Targets (Hardcover)
Loot Price: R4,390
Discovery Miles 43 900
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Proteinases as Drug Targets (Hardcover)
Series: Drug Discovery, Volume 18
Expected to ship within 10 - 15 working days
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This unique book describes newly discovered proteolytic enzymes and
their biological function. In many cases, these enzymes are targets
for new drug discovery in order to provide new therapeutic
approaches to control human diseases and/or metabolic conditions.
The chapters in this book will help other investigators to pursue
drug discovery by detailing methods of production and assay of the
enzymes. In addition, the latest structural studies that are
described in the book will permit rapid advances in drug design.
The most important elements of this book are the state-of-the-art,
detailed descriptions of the properties of the proteolytic enzymes.
The chapters in the book, written by leading experts in the field,
collect the best work on the topics with complete bibliographies
for each target enzyme. The illustrations are highly informative to
aid and facilitate a new design of inhibitors that can be developed
as drug candidates. Key chapters include those by Mark Gorrell and
Catherine Abbott, both describing dipeptidyl peptidases, which have
been implicated in a number of metabolic conditions including
diabetes. The chapters are written from two very different
perspectives, thus enriching the literature in this area. In
addition, the chapter by Sheena McGowan focuses on aminopeptidases
from the malaria parasite, Plasmodium falciparum, and the chapter
by Ben Dunn deals with the aspartic peptidases from the same
organism.
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