Targeting Cell Survival Pathways to Enhance Response to Chemotherapy, Volume 3 (Hardcover)

Targeting Cell Survival Pathways to Enhance Response to Chemotherapy encompasses recently developed molecular targeting agents and approaches that suppress cell survival signaling. Cell survival signaling attenuates the effectiveness of conventional chemotherapy and numerous mechanisms have been described, and continue to be described, which contribute to cell survival in the face of chemotherapy treatment. Key pathways leading to chemoresistance emanate from growth factor receptors, PI3K, STAT3, anti-apoptotic Bcl-2 family members, autophagy, and the DNA damage response pathway. New advances have underscored the potential of targeting each of these cell survival mechanisms to improve responsiveness to chemotherapy. This book reviews these recent advances and provides a foundational background and hints of new opportunities for basic, translational, and clinical investigators focused on improving therapeutic responses to chemotherapy.

General

Imprint:	Academic Press Inc
Country of origin:	United States
Series:	Cancer Sensitizing Agents for Chemotherapy
Release date:	March 2018
First published:	2019
Series editors:	Benjamin Bonavida
Volume editors:	Daniel E. Johnson
Dimensions:	235 x 191mm (L x W)
Format:	Hardcover
Pages:	308
ISBN-13:	978-0-12-816432-7
Categories:	Books > Medicine > General issues > Public health & preventive medicine > Personal & public health > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General Promotions
LSN:	0-12-816432-8
Barcode:	9780128164327

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