Diarrhoeal disease is a major health problem throughout the world,
and is responsible for high morbidity and mortality mainly among
children and especially in developing countries like Nepal. This
cross-sectional prospective study was designed to determine the
incidence of Cholera, Shigellosis and Salmonellosis along with
screening of the possible extended spectrum -lactamase producer
among multi-drug resistant isolates from 268 diarrhoeal patients
visiting different hospitals of Kathmandu valley and 5 other
districts of Nepal in the period of April 2010 to January 2011. The
specimens were processed by standard microbiological methods and
confirmed with serology. Bacteria have been found as one of the
common causes of diarrhoea and Cholera as one of the major reasons
of diarrhoea. This study indicates a continuing need for resistance
surveillance and rational use of antimicrobial agents to reduce the
multi-drug resistance."
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