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Microanatomy and Function of the Spleen (Paperback, Softcover reprint of the original 1st ed. 2000)
Loot Price: R4,431
Discovery Miles 44 310
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Microanatomy and Function of the Spleen (Paperback, Softcover reprint of the original 1st ed. 2000)
Series: Advances in Anatomy, Embryology and Cell Biology, 151
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5 Function of Splenic Compartments . . . . . . . . . . . . . . . 45
5. 1 Splenic White Pulp Compartments during Primary T
Cell-Dependent Antibody Responses against Protein Antigens . . . .
. . . . . . . . . . . . . . . . . . . . . 46 5. 1. 1 Priming of
CD4+ Helper T Cells by Dendritic Cells in the PALS . . . . . . . .
. . . . . . . . . . . . 46 Summary . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . 49 5. 1. 1. 1 5. 1. 2
Interaction of Primed CD4+ T Cells with Antigen-Specific B Cells in
the PALS and Formation of Extrafollicular Foci . . . . . . . . . .
. . . . . . . . . . . . . . . . . 49 5. 1. 2. 1 Summary . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 50
5. 1. 3 Formation of Germinal Centres . . . . . . . . . . . . . . .
. . . . 50 5. 1. 3. 1 Summary . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . 55 5. 1. 4 Localisation of
Memory B Cells in the Marginal Zone . . . . . . . . . . . . . . . .
. . . . . . . . . . . . 55 5. 1. 4. 1 Summary . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . 57 5. 2
Function of the Marginal Zone during Primary Antibody Responses
against T Cell-Independent Type 2 Antigens . . . . . . . . 57 5. 2.
1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . 59 Function of the Red Pulp . . . . . . . . . . .
. . . . . . . . . . . . . . 59 5. 3 5. 3. 1 Summary . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61 5. 4
Role of the Spleen in CD8+ Cytotoxic T Cell Responses . . . . . . .
. . . . . . . . 61 5. 4. 1 Summary . . . . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . 62 The Spleen, Natural
Killer Cells 5. 5 and Gamma/Delta T Cells . . . . . . . . . . . . .
. . . . . . . . . . . 62 5. 5. 1 Summary . . . . . . . . . . . . .
. . . . . . . . . . . . . . . . . . . . . . . . . 63 6
Recirculation of Lymphocytes Through the Spleen . . 65 6. 1 Summary
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . 67 7 The Role of Cytokines and Chemokines in the
Development of Splenic Compartments . . . . . . 69 7. 1 Summary . .
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. . 72 8 Unsolved Problems of Human Splenic Structure and Function
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
. 73 VI 8. 1 Arterial Blood Supply to the Splenic Follicles and to
the Perifollicular Zone. . . . . . . . . . . . . . . . . 73 . . . .
8. 1. 1 Summary . . . . . . . . . . . . . . . . . . . . . . . . . .
. . . . . . . . . . . . 74 8.
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