As one of many tasks of an analytical chemistry program sponsored
by the office of Pesticides and Toxic Substances, Field Studies
Branch, U.S. Environmental Protection Agency (EPA) (EPA Prime
Contract No. 68-02-3938), Midwest Research Institute (MRI) prepared
these summaries of the mammalian toxicology of 52 individual
elements (metals and metalloids) and the lanthanides (rare earth
elements). MRI is assisting the EPA in developing protocols for the
monitoring of selected metals and organic compounds in the blood of
the general U.S. population. The monitoring will enable evaluation
of changes in the blood levels over time and any trends associated
with instituted control measures. This review will help EPA select
the metals to be included in the monitoring effort based on
toxicity, relative exposure, and the ability of blood measurements
to reflect exposure.
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