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Advanced Methods in Protein Microsequence Analysis (Paperback, Softcover reprint of the original 1st ed. 1986)
Loot Price: R2,986
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Advanced Methods in Protein Microsequence Analysis (Paperback, Softcover reprint of the original 1st ed. 1986)
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Much of the recent spectacular progress in the biological sciences
can be at tributed ot the ability to isolate, analyze, and
structurally characterize proteins and peptides which are present
in cells and cellular organelles in only very small amounts. Recent
advances in protein chemistry and in particular the application of
new micromethods have led to fruitful advances in the understanding
of basic cellular processes. Areas where protein-chemical studies
have resulted in interest ing discoveries include the peptide
hormones and their release factors, growth factors and oncogenes,
bioenergetics, proton pumps and ion pumps and chan nels,
topogenesis and protein secretion, molecular virology and
immunology, membrane protein analysis, and receptor research. In
fact, the key methods are now on hand to unravel many of the major
outstanding problems of molecular biology and in particular
questions of fundamental interest which relate to devel opmental
biology and specificity in cell-cell interaction. In this volume we
have assembled descriptions of procedures which have re cently been
shown to be efficaceous for the isolation, purification, and
chemical characterization of proteins and peptides that are only
available in minute amounts. Emphasis is placed on well-established
micromethods which have been tested and found useful in many
laboratories by experienced investigators. The chapters are written
by specialists, and describe a range of sensitive techniques which
can be used by researchers working in laboratories with only modest
resources and equipment."
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