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Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products (Hardcover, 1979 ed.)
Loot Price: R3,122
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Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products (Hardcover, 1979 ed.)
Series: Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products, 36
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Since the late 1950's when proton n. m. r. spectroscopy was first
used in organic natural products studies the technique has
increasingly con of this important area of chemistry. tributed to
the rapid advancement Although the potential utility of 13C n. m.
r. was recognized very early, essentially no application of 13C n.
m. r. appeared in the literature prior to 1966 and 95% of the
existing data are less than five years old. The initially slow
growth had its cause in inadequate instrumentation, insufficient
sensitivity being the main obstacle. This situation drastically
changed with the advent and commercial availability of broadband ex
citation and Fourier transform methods, giving natural-abundance
13C n. m. r. and its numerous chemical applications a tremendous
impetus. Today BC spectra can be recorded on sample quantities down
to the submilligram level, which until recently even withstood
proton n. m. r. Paralleling the development of experimental
techniques considerable progress has also been made on an
understanding of spectral parameters, in particular their
stereochemical implications on natural products. Although the large
majority of data present up to now deals with known structures, an
adequate basis now exists which allows the chemist to use the
technique for tackling real problems on unknown molecules."
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