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The Pathogenic Enteric Protozoa: - Giardia, Entamoeba, Cryptosporidium and Cyclospora (Hardcover, 2004 ed.)
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The Pathogenic Enteric Protozoa: - Giardia, Entamoeba, Cryptosporidium and Cyclospora (Hardcover, 2004 ed.)
Series: World Class Parasites, 8
Expected to ship within 10 - 15 working days
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Giardia duodenalis (=G. lamblia), Entamoeba histolytica,
Cryptosporidium parvum and Cyclospora cayetanensis are more than
just a mouthful for most who might encounter them. These protozoan
parasitic agents contribute significantly to the staggering
caseload of diarrheal disease morbidity encountered in developing
world nations. Compounding the issue of their mere presence is the
fact that standard ova and parasite exams frequently do not detect
these infections. Detectable stages may be shed intermittently or
require specialized staining procedures. Added to this is the often
large number of asymptomatic carriers who serve as reservoirs for
infecting others. These parasites are also not strangers to more
developed nations, having responsibility for both small and
large-scale disease outbreaks. In such settings they may be even
more difficult to detect simply because they are frequently
overlooked in the grand scheme of disease causing possibilities.
They share common features; all are Protozoa, all possess trophic
stages that inhabit the gastrointestinal tract, all have the
ability to produce disease and in some instances death, and all
produce environmentally stable cysts or oocysts, which ensure their
transmissibility. In other ways, these organisms are profoundly
different. Giardia is a flagellate that inhabits the gut lumen in
close association with enterocytes. Entamoeba is an amoeba that
preferentially inhabits the mucosal region of the gut lumen, but
which may, under certain circumstances, become invasive.
Cryptosporidium and Cyclospora are obligate intracellular
coccidians, each taking up a unique niche within their respective
host enterocytes.
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