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Books > Medicine > Clinical & internal medicine > Diseases & disorders
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Is Crohn's Disease a Mycobacterial Disease? (Hardcover, 1992 ed.)
Loot Price: R2,957
Discovery Miles 29 570
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Is Crohn's Disease a Mycobacterial Disease? (Hardcover, 1992 ed.)
Series: Developments in Gastroenterology, 14
Expected to ship within 10 - 15 working days
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Total price: R2,977
Discovery Miles: 29 770
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IS CROHN'S DISEASE A MYCOBACTERIAL DISEASE'! The fact that the
differential diagnosis of inflammatory bowel disease includes
intestinal infections has been a source of much interest and
clinical concern for many years. Since the recognition of
ulcerative colitis and Crohn's disease as clinical entities,
numerous attempts have been made to identify a specific organism
resulting in the clinical and pathologic picture of Inflammatory
Bowel Disease. The first suggestion about a connection between
Johne's disease, a chronic mycobacterial enteritis in cattle, and
Crohn' s disease occurred in 1913, when Dalziel described enteritis
in humans which, although resembling intestinal tuberculosis, he
believed to be a new disorder. Since the work of Crohn in the
thirties a few investigators attempted to look for mycobacteria in
Crohn's disease. Until now the work of Van Patter, Burnham and
others did not receive widespread recognition. In 1984 the
isolation of M. paratuberculosis was reported by Chiodini et al.
This report initiated the current interest and controversy about a
mycobacterial etiology in Crohn's disease. The hypothesis "Crohn's
disease is Johne's disease" did not receive widespread recognition,
but has lead to the first muIticentered efforts to determine
whether or not mycobacteria are associated with Crohn's disease.
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