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Books > Social sciences > Psychology > Physiological & neuro-psychology
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The Behavioral Neurology of White Matter (Hardcover, 2nd Revised edition)
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The Behavioral Neurology of White Matter (Hardcover, 2nd Revised edition)
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Behavioral neurology is founded on lesions of cortical gray matter,
but recently the contributions of cerebral white matter to
cognitive and emotional dysfunction have also attracted attention.
The Behavioral Neurology of White Matter surveys this broad and
fascinating field from a clinical perspective. Stimulated by recent
improvements in neuroimaging, white matter has been carefully
studied, and its role in the operations of cognition and emotion
clarified by correlations with clinical observations. The relevance
of normal and abnormal white matter to behavioral neurology is
apparent in every context where this question has been examined: in
development, aging, and in a host of diseases, intoxications, and
injuries. Since the first edition of this book in 2001, steady
advances have been made in understanding the neurobiology of white
matter and its clinical significance; this edition provides a
comprehensive update on this rapidly expanding field. Every chapter
has been extensively rewritten, including a comprehensive revision
of the account of the neuropsychiatry of white matter, a
particularly challenging area. The syndrome of white matter
dementia is discussed in detail, and its refinement with new
information is considered along with the proposal of mild cognitive
dysfunction as a precursor syndrome in many clinical settings. In
addition, two new chapters have been added, one on the emerging
area of white matter changes associated with neurodegenerative
disorders such Alzheimer's Disease, and another on neurologic
aspects of white matter including intriguing new information on
white matter plasticity. A unifying theme is the concept of
connectivity, as it is clear the white matter forms an essential
component of the widespread distributed neural networks by which
cognition and emotion are organized. In addition to the
microconnectivity within gray matter that subserves information
processing, the macroconnectivity of white matter enables
information transfer - both are critical for the functions of the
human mind.
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