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Randomised Controlled Clinical Trials (Paperback, Softcover reprint of the original 1st ed. 1983)
Loot Price: R2,783
Discovery Miles 27 830
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Randomised Controlled Clinical Trials (Paperback, Softcover reprint of the original 1st ed. 1983)
Series: Developments in Biostatistics and Epidemiology, 1
Expected to ship within 10 - 15 working days
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Bradford Hill has defined a clinical trial as "A carefully and
ethically designed experiment with the aim of answering some
precisely framed question" 1]. This definition specifies a careful
design and requires the provision of adequate controls. Random
allocation of treatments to subjects is important to ensure is
entitled that the treated and control groups are similar. Therefore
this book Randomised Controlled Clinical Trials. We can define a
randomised controlled trial by rewriting Bradford Hill's definition
as follows, "A carefully and ethi cally designed experiment which
includes the provision of adequate and ap propriate controls by a
process of randomisation, so that precisely framed questions can be
answered. " I am a firm advocate ofRandomised Controlled Clinical
Trials but intend to give a balanced view of the advantages and
disadvantages of these ethical experiments. This book is directed
primarily at the medical research worker, although certain chapters
may find a wider application. When discussing a randomised
controlled trial, it is neither practicable nor desirable to
divorce theory from practice, however the first ten chapters con
centrate mainly on theory, and the remainder focus on practice. The
segment on trial design is followed by sections on writing the
protocol, designing the forms, conducting the trial, and analysing
the results. This book is meant to serve both as a reference manual
and a practical guide to the design and performance of a trial."
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