The biochemistry and cell biology of Matrix Metalloproteinases
(MMPs) are not necessarily straightforward, but basic information
on the history of these enzymes, their various functions that
extend far beyond the cleaving of the extracellular matrix, and the
complex mechanisms that control their expression are valuable to
both scientists and clinicians. This volume summarizes the salient
features and functions of MMPs and applies this information in a
practical manner in order to understand how they contribute to
normal physiology and pathology of selected diseases. Chapters by
noted clinicians Jean-Michel Dayer, MD in rheumatology, Jian Cao,
MD in oncology, and Peter Libby, MD in cardiology, represent
important practical and clinically-oriented contributions.
General
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