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Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics
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Homing Endonucleases - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2014)
Loot Price: R4,278
Discovery Miles 42 780
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Homing Endonucleases - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2014)
Series: Methods in Molecular Biology, 1123
Expected to ship within 10 - 15 working days
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Homing Endonucleases: Methods and Protocols aims at providing
molecular biologists with a comprehensive resource to identify and
characterize homing endonucleases from genomic sequence, to deduce
the biological basis of binding and cleavage specificity, as well
as to provide protocols to redesign endonuclease target specificity
for genome-editing applications. Engineering of designer homing
endonucleases has set the stage for genome editing of complex
eukaryotic genomes with a broad range of potential applications
including targeted gene knockouts in model organisms and gene
therapy in humans, making this book a valuable resource for future
research. Written in the highly successful Methods in Molecular
Biology series format, chapters include introductions to their
respective topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols and tips on
troubleshooting and avoiding known pitfalls. Authoritative and
practical, Homing Endonucleases: Methods and Protocols serves as a
key reference for all labs studying site-specific DNA
endonucleases.
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