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Books > Medicine > General issues > Medical equipment & techniques > Medical research
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The Use of Restricted Significance Tests in Clinical Trials (Hardcover, 1992 ed.)
Loot Price: R1,706
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The Use of Restricted Significance Tests in Clinical Trials (Hardcover, 1992 ed.)
Series: Statistics for Biology and Health
Expected to ship within 10 - 15 working days
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The reader will soon find that this is more than a "how-to-do-it"
book. It describes a philosophical approach to the use of
statistics in the analysis of clinical trials. I have come
gradually to the position described here, but I have not come that
way alone. This approach is heavily influenced by my reading the
papers of R.A. Fisher, F.S. Anscombe, F. Mosteller, and J. Neyman.
But the most important influences have been those of my medical
colleagues, who had important real-life medical questions that
needed to be answered. Statistical methods depend on abstract
mathematical theorems and often complicated algorithms on the
computer. But these are only a means to an end, because in the end
the statistical techniques we apply to clinical studies have to
provide useful answers. When I was studying martingales and
symbolic logic in graduate school, my wife, Fran, had to be left
out of the intellectual excitement. But, as she looked on, she kept
asking me how is this knowledge useful. That question, what can you
do with this? haunted my studies. When I began working in bio
statistics, she continued asking me where it was all going, and I
had to explain what I was doing in terms of the practical problems
that were being ad dressed."
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