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Practical Toxicology - Evaluation, Prediction, and Risk, Third Edition (Hardcover, 3rd edition)
Loot Price: R2,434
Discovery Miles 24 340
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Practical Toxicology - Evaluation, Prediction, and Risk, Third Edition (Hardcover, 3rd edition)
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Practical Toxicology: Evaluation, Prediction, and Risk, Third
Edition shows how to conduct a program of safety evaluation and
testing and then to interpret and apply the resulting data and
information in the real world, beginning with the basic concepts in
toxicology and progressing to the interpretation of the resulting
data. Revised and updated chapters on risk assessment guide the
reader to setting the foundations necessary for submission to
regulatory authorities. In addition, a new chapter in the book
reviews the errors in toxicology, mistakes, misuse, mismanagement,
and misunderstanding with a view to avoiding these in the future.
New Chapters in the Third Edition: Toxicology in silico Errors in
Toxicology Safety Assessment of Extractables and Leachables. This
new edition follows a practical sequence from introducing the
basics of toxicology (including the vital concept of normality in
controls) to describing a test program and then interpreting the
data and translating that to risk assessment that can be used in a
number of real world situations where safety and secure risk
assessment are essential. Although written primarily from the
perspective of pharmaceutical development, the test designs and
toxicological problems encountered in that field are entirely
relevant to those with other classes of chemicals, the only
difference being the regulatory context. Toxicology is an
international discipline and the book has been written to take into
account some of the differences in regulatory nuance between the
main regions of the world. Completely revised and written in an
easily accessible style, the text address several audiences-from
students and post-graduates coming to the subject for the first
time to established professionals who find themselves needing to
learn about toxicology, toxicity testing, interpretation of the
results, and risk assessment. It is intended primarily as a
textbook, with case studies and information on where to go to ask
questions, but can also be used as a practical reference book. It
covers all the basics of toxicology and the main aspects of safety
evaluation testing and risk assessment while reviewing critically
the current state of the discipline. It also provides a foundation
for those seeking registration or certification.
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