Early detection is critical for any given cancer. With the advent
of the latest omics technologies, molecular markers in combination
with conventional diagnostic and screening methods are emerging as
next-generation early diagnostic and prognostic strategies that can
allow early-stage diagnosis, resulting in more effective treatment
and patient care and, in turn, an increased rate of survival. A
ready-made resource, Noninvasive Molecular Markers in Gynecologic
Cancers not only provides information on noninvasive molecular
diagnostic biomarkers, it includes coverage of the epidemiology,
clinical features, conventional diagnosis, treatment, and prognosis
for these cancers. With contributions from leading international
experts, the book presents a compact but comprehensive overview of
gynecologic cancer. Each of the five main gynecologic
cancers-ovarian, cervical, uterine, vaginal, and vulvar-have unique
signs and symptoms, risk factors, and molecular profile, and
therefore requires different prevention strategies. This book
describes the different features of each gynecologic cancer in
separate chapters covering general information, epidemiology,
clinical features, and biomarkers. The book also covers breast
cancer and, although rare, fallopian tube cancer, to make it a
complete resource. In cancer treatment, non-invasive diagnosis can
avoid complications of biopsy and other unfavorable impacts on
patients' health. DNA, methylation, SNPs, miRNA, mRNA, protein,
autoantibodies, metabolite, and omics-based markers from remote
media such as blood, plasma, and urine are emerging as noninvasive
molecular markers with high specificity and sensitivity towards
many cancers. This book classifies the available molecular tumor
markers according to their principal characteristics and relative
methodologies. It covers markers that not only provide early
detection and better treatment options, but are emerging as
next-generation personalized diagnostics and targets or
therapeutics for personalized cancer treatment.
General
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