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Progressive Multifocal Leukoencephalopathy - Risk Factors, Management Strategies & Prognosis (Hardcover)
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Progressive Multifocal Leukoencephalopathy - Risk Factors, Management Strategies & Prognosis (Hardcover)
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Progressive multifocal leukoencephalopathy (PML) is a rare,
disabling and potentially fatal brain infection of the central
nervous system (CNS) caused by reactivation of the John Cunningham
virus (JCV). The most important risk factor for PML is
immunosuppression associated with HIV/AIDS or therapy.
Approximately 60 to 80% of the adult population has JC antibodies,
but PML is rarely diagnosed. The chapters in this book include
research on the pathologic features of PML, the diagnosis, risk
factors, pathogenesis, and management strategies.
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