This book sets out the unique and paradoxical position biomedical
science finds itself in, in the early 21st (superscript st)
century. Science has never been stronger in shaping the world we
live in; progress in medical science during most of the last
century has helped to transform health care and prolong our lives;
almost daily advances in biological science promise hope for the
future and yet medical science has been in serious decline for the
past three decades.Biomedical Science in the 21st (superscript st)
Century: Sunset or New Dawn? sets out the recent decline in the
context of medical science's stunning past successes. Professor
Sheridan discusses the failure to translate new discoveries in
biological science into medical advances; the dramatic decline in
research productivity in the pharmaceutical industry in the context
of falling numbers of clinical scientists; the disruption of
medical science during prolonged and repeated reforms of health
care delivery; changing social and political attitudes towards
health care and science; the loss of trust in big pharmaceutical
companies and recent revelations of fraud in science. The book
deals with the creative nature of original science, how it is
driven by curiosity and self-motivation and how these can be
stifled by pettifogging managerialism.The book presents a vision of
what medical science can deliver during the coming half century and
what is needed to overcome the present challenges. It questions the
assumptions that big is best in the organisation of science and
suggests a new model for drug development based on a restoration of
trust and a more constructive relationship between regulators and
industry.
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