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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical) > DNA
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Transposons and the Dynamic Genome (Hardcover, 2009 ed.)
Loot Price: R4,359
Discovery Miles 43 590
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Transposons and the Dynamic Genome (Hardcover, 2009 ed.)
Series: Genome Dynamics and Stability, 4
Expected to ship within 10 - 15 working days
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It will be some time beforewe see Relax, there's nothing wrong with
the "slime, protoplasm, &c. "generating transpositionpaper.
People aren't a new animal. ButI have long readyforthisyet.
Istopped publishing regretted that I truckled to public in refereed
journals in 1965 because opinion,andusedthePentateuchal therewas
nointerest in themaize term of creation,by which I really
controlling elements. meant "appeared" by some wholly Barbara
McClintockto Mel Green, unknownprocess. It is mere rubbish, 1969
thinking at presentof theorigin of life; onemight as well think of
the originof matter. Charles Darwin to James D. Hooker, March29,
1863 Sometimes my students and others have asked me: "what was ?rst
in evo- tion - retroviruses or retrotransposons?" Since HowardTemin
proposed that
retrovirusesevolvedfromretrotransposons(Temin1980;Teminetal.
1995)the other alternative that retroviruses emerged ?rst and were
the predecessors of LTR-retrotransposons has since been a
controversial issue (Terzian et al. , this BOOK). While
DNA-transposons could not have existed in an ancestral R- world by
de?nition, sure enough, some arguments de?nitely point towards
apre-DNAworldscenarioinwhichretroelementswerethedirectdescendants
of the earliest replicators representing the emergence of life.
First, these rep- cators likely catalyzed their own or other's
replication cycles via the catalytic properties of RNA molecules.
After translation had emerged some replicators possibly encoded an
RNA polymerase ?rst. This later evolved into reverse
transcriptase(RT),i. e.
themostprominentkey-factoratthetransitionintothe DNA world.
Simultaneously, replicators could also have encoded membrane
protein-genessuchastheenvgeneofrecentDNA-proviruses. Membraneswere
likely present muchearlier as prebioticoily ?lms that supported
theevolution of a prebiotic-protometabolism (Dyson 1999; Grif?ths
2007).
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