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Books > Medicine > Pre-clinical medicine: basic sciences > Anatomy
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Ultrastructure of Skeletal Tissues - Bone and Cartilage in Health and Disease (Hardcover, 1990 ed.)
Loot Price: R7,138
Discovery Miles 71 380
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Ultrastructure of Skeletal Tissues - Bone and Cartilage in Health and Disease (Hardcover, 1990 ed.)
Series: Electron Microscopy in Biology and Medicine, 7
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The calcified tissues have fundamental functions in the biology of
organisms, not only because their strength, solidity, and
elasticity permit movement and mechanical activities, and protect
soft tissues against traumatic forces, but also on account of their
role in mineral homeostasis. For this reason, extensive
investigation in the last 30 years has provided much to explain the
complex chemical and physical processes occurring in cells and
matrices composing the skeleton, and their alterations in
pathological conditions. The use of ultrastructural methods such as
immunocytochemistry, scanning and transmission electron microscopy,
cytoautoradiography, freeze/fracture etching, high voltage, etc.
has proven to be of great value when applied to cells and matrix
components of bone and cartilage, in spite of the technical
difficulties due to the hardness of these tissues. However,
available information on this subject is disseminated in a variety
of scientific and medical articles. This volume is an attempt to
collect together the most significant data on the ultrastructure of
cartilage and bone in normalcy and pathology. Obviously, it cannot
be a complete report of all these data, its principal aim being
that of: a) giving a comprehensive statement of the results
concerning the basic structures common to these tissues, especially
collagen fibrils, noncollagenous proteins, and proteoglycans, and
their relationships with the mineral substance (for which another
volume of this series can also be consulted; see Ruggeri A. , Motta
P. M. (eds.
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