Post-traumatic stress disorder (PTSD) arises from the experience of
severe stressors and trauma. The disorder is characterized by
recurrent recall of intrusive memories to the event, nightmares
with insomnia, emotional numbing, hyperarousal, which are all
long-lasting and relatively resistant to therapy. The focus of this
book is on the question of how stress hormones are involved in
PTSD. Recent evidence suggests that a dysregulation in stress
hormones promotes the precipitation of PTSD and that correction of
these hormones may ameliorate the disorder. This book combines
state-of-the-art basic research on stress hormones from gene to
behaviour with clinical research demonstrating the progress in
understanding via imaging techniques, genetics, vulnerable
phenotypes and co-morbidity with other disorders and physical
illness.
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