It's in Your DNA: From Discovery to Structure, Function and Role in
Evolution, Cancer and Aging describes, in a clear, approachable
manner, the progression of the experiments that eventually led to
our current understanding of DNA. This fascinating work tells the
whole story from the discovery of DNA and its structure, how it
replicates, codes for proteins, and our current ability to analyze
and manipulate it in genetic engineering to begin to understand the
central role of DNA in evolution, cancer, and aging. While telling
the scientific story of DNA, this captivating treatise is further
enhanced by brief sketches of the colorful lives and personalities
of the key scientists and pioneers of DNA research. Major
discoveries by Meischer, Darwin, and Mendel and their impacts are
discussed, including the merging of the disciplines of genetics,
evolutionary biology, and nucleic acid biochemistry, giving rise to
molecular genetics. After tracing development of the gene concept,
critical experiments are described and a new biological paradigm,
the hologenome concept of evolution, is introduced and described.
The final two chapters of the work focus on DNA as it relates to
cancer and gerontology. This book provides readers with much-needed
knowledge to help advance their understanding of the subject and
stimulate further research. It will appeal to researchers,
students, and others with diverse backgrounds within or beyond the
life sciences, including those in biochemistry, genetics/molecular
genetics, evolutionary biology, epidemiology, oncology,
gerontology, cell biology, microbiology, and anyone interested in
these mechanisms in life.
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