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Proteomics and Nanocrystallography (Hardcover, 2003 ed.)
Loot Price: R2,940
Discovery Miles 29 400
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Proteomics and Nanocrystallography (Hardcover, 2003 ed.)
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The book addresses the most recent developments in structural and
functional proteomics underlying the recent contributions given in
these areas by our laboratory to the instrumentations, the methods
and the procedures as mutuated from the nanoscale sciences and
technologies. These developments introduced in the last few years
make now possible protein massive identification (mass spectrometry
and biomolecular arrays down to nanoamounts) and protein structural
characterization in solution and in crystals down to the atomic
scale to an extent and to a degree so far unmatched. Emphasis is
placed in the growth by nanobiofilm template of protein crystals of
any type and size from millimeter to micron, leading in combination
with microfocus synchrotron technology and atomic force microscopy
to the definition of a new field called nanocrystallography. The
few useful examples being shown, concerning yet structurally
unsolved proteins, point this very promising approach
nanotechnology-based in structural proteomics using highly focused
X-rays. This has not to be confused with the important study of
nanocrystals, both organic and inorganic, and novel diamond like
nanocomposite materials and devices having 3D protein crystals as
matrices to be equilibrated with nanoparticles/gold/silver to be
utilized in the most diversified electronic applications here also
summarized. vii Acknowledgments We are particularly grateful to
Giuseppe Zanotti at the University of Padova for his fundamental
collaboration during all the crystallographic studies.
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