Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Fibrinolytics and Antifibrinolytics (Hardcover)
Loot Price: R2,632
Discovery Miles 26 320
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Fibrinolytics and Antifibrinolytics (Hardcover)
Series: Handbook of Experimental Pharmacology, v. 146
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This book covers basic aspects of the molecular biology,
biochemistry and pharmacology of the plasminogen-plasmin
(fibrinolytic) system. Individual chapters, written by well-known
experts in the field, are devoted to plasminogen and its
activation, the tissue-type plasminogen activator (tPA), the
urinary-type-plasminogen activator (uPA), inhibitors of the
fibrinolytic system, and the assembly of fibrinolytic constituents
on cell surfaces. The major part of the book deals with the
therapeutic use of thrombolytic agents in myocardial infarction,
deep venous thrombosis, pulmonary embolism, peripheral arterial
occlusions and stroke. The newest thrombolytic agents are discussed
in depth. Results of major clinical trials up to the end of 1999
are critically evaluated. The volume is a modern up-to-date
presentation of the entire field of the treatment of arterial and
venous thromboses with thrombolytic agents.
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