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The Collagen Superfamily and Collagenopathies (Hardcover, 1st ed. 2021)
Loot Price: R4,382
Discovery Miles 43 820
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The Collagen Superfamily and Collagenopathies (Hardcover, 1st ed. 2021)
Series: Biology of Extracellular Matrix, 8
Expected to ship within 12 - 17 working days
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This book aims at providing insights into the collagen superfamily
and the remarkable diversity of collagen function within the
extracellular matrix. Additionally, the mechanisms underlying
collagen-related diseases such as dystrophic epidermolysis bullosa,
osteogenesis imperfecta, as well as collagen-related myopathies and
neurological disorders are discussed. Collagens are the most
abundant extracellular matrix proteins in organisms. Their primary
function is to provide structural support and strength to cells and
to maintain biomechanical integrity of tissues. However, collagens
can no longer be considered just as structural proteins. They can
act as extracellular modulators of signaling events and serve
critical regulatory roles in various cell functions during
embryonic development and adult homeostasis. Furthermore, collagens
are associated with a broad spectrum of heritability-related
diseases known as "collagenopathies" that affect a multitude of
organs and tissues including sensorial organs. The book is a useful
introduction to the field for junior scientists, interested in
extracellular matrix research. It is also an interesting read for
advanced scientists and clinicians working on collagens and
collagenopathies, giving them a broader view of the field beyond
their area of specialization.
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