Books > Medicine > Clinical & internal medicine > Renal medicine
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Primary & Secondary Glomerulonephritis - Signs, Symptoms & Treatment (Hardcover)
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Primary & Secondary Glomerulonephritis - Signs, Symptoms & Treatment (Hardcover)
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Glomerulonephritis is a term referring to direct injury of the
glomeruli with resulting disturbances of normal glomerular
function, progressively leading to renal failure. Glomerular
diseases are classified as primary, where glomerular damage is the
prime disturbance, with extrarenal manifestations as a result of
renal impairment, and secondary, following systemic disorders,
infections or exposure to certain drugs. Although noteworthy
progress has been made in the past years in the symptomatic and
specific treatment, therapy of both primary and secondary
glomerulonephritis can be challenging. Management of these patients
requires early diagnosis, expert knowledge of the immunosuppressive
agents and other drugs currently available for the treatment of
each glomerulonephritis, consideration of possible adverse
reactions to these drugs, alternative therapeutic strategies in
cases of hyporesponsiveness or non-responsiveness of the patient to
the treatment, and possible relapses of the disease. This book
reviews knowledge of the main primary and secondary
glomerulonephritis, with emphasis on current therapeutic strategies
and practical recommendations. Glomerulonephritis are grouped
according the presence or absence of proliferative histological
alternations into primary and secondary proliferative and
non-proliferative types. Each chapter deals with etiopathogenesis,
epidemiology, pathology, clinical manifestations, natural history
and therapeutic options of the commonest primary and secondary
glomerular diseases, with exception the last chapter that covers
inherited diseases with renal involvement. An atlas of the
pathology of the glomerular diseases discussed completes this work.
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