Molecular Aspects of G Protein-Coupled Receptors - Interacting Proteins & Function (Hardcover, Illustrated Ed)

In the recent years, studies based on two-hybrid screens, proteomic, biochemical and cell biology approaches, have shown that intracellular domains of G protein-coupled receptors (GPCR) or heptaspanning membrane receptors (HSMRs) interact with intracellular proteins. These interactions are the basis of a protein network associated to these receptors which includes scaffolding proteins containing one or several PDZ (post-synaptic density-95, discs large, zona occludens-1) domains, signalling proteins and proteins of the cytoskeleton. The present book is focused on the emerging evidence for interactions of G protein-coupled receptors with scaffolding, cytoskeletal and signalling proteins that will play a role in the targeting, anchoring and functioning of these receptors in the plasma membrane, thus contributing to cell development and plasticity.

General

Imprint:	nova science publishers
Country of origin:	United States
Release date:	November 2007
Editors:	Franciso Ciruela • Rafael Lujan
Dimensions:	180 x 260 x 25mm (L x W x T)
Format:	Hardcover
Pages:	309
Edition:	Illustrated Ed
ISBN-13:	978-1-60021-915-3
Categories:	Books > Science & Mathematics > Biology, life sciences > Biochemistry > Proteins Promotions
LSN:	1-60021-915-2
Barcode:	9781600219153

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