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Proteoglycans - Methods and Protocols (Hardcover, 2012)
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Proteoglycans - Methods and Protocols (Hardcover, 2012)
Series: Methods in Molecular Biology, 836
Expected to ship within 12 - 17 working days
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Now recognized as a reservoir for growth factors and cytokines
modulating cell activation status and turnover, proteoglycans have
stimulated great amount of interest and research. In Proteoglycans:
Methods and Protocols, experts in the field examine issues of basic
concepts and up-to-date analysis methods for proteoglycan and
glycosaminoglycan (GAG) at the protein and saccharide levels. The
volume continues with the multifunctional aspect of proteoglycans,
highlighted through three relevant examples of proteoglycans with
highly different strucutures: serglycin, aggrecan, and heparin
sulphate proteoglycans. The final chapter describes proteoglycan
involvement in the pathogenesis of various disorders and their
potential therapeutic value in osteo-articular diseases. Written in
the highly successful Methods in Molecular Biology (TM) series
format, chapters include introductions to their respective topics,
lists of the necessary materials and reagents, step-by-step,
readily reproducible laboratory protocols, and tips on
troubleshooting and avoiding known pitfalls. Authoritative and
accessible, Proteoglycans: Methods and Protocols is an ideal guide
for scientists attempting to pursue further research in this vital
and complex area of study.
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