Advances in Immunology, Volume 61 (Hardcover)

"The series which all immunologists need."
--The Pharmaceutical Journal
"Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions."
--Science
"Deserves a permanent place in biomedical libraries as an aid in research and in teaching"
--Journal of Immunological Methods
"A provocative and scholarly review of research"
--Journal of the American Medical Association
"Provides an extremely valuable source of reference and many stimulating ideas...the main repository of information in a rapidly devloping subject"
--The Lancet
"Provides unrivalled value in both academic and fiscal terms and should be purchased by hard pressed librarians as a major priority to be jealously defended."
--Journal of Medical Microbiology
"A very valuable serial publication...no serious student of immunology can afford to be without it."
--Archives of Biochemistry and Biophysics

Key Features
* Focus on components of the V(D)J recombination machinery that might be related to diseases in humans and animals
* Control of the complement system by control of C3/C5 convertase on host cells, control of fluid phase C3/C5 convertases, control of fluid phase MAC, and control of deposited MAC
* Immunodeficiency resulting from a complete absence of MHC class II expression and two trans-acting factors controlling transcription
* Current knowledge of IL-2R signaling, highlighting IL-2 signaling, and T-cell growth regulation
* Functional role of CD40 in cells, the "in vivo" significance of CD40-CD40-L interactions, and the signal transduction machinery activated following crosslinking of the CD40 antigen
* Integrative approach to better understand the observed heterogeneity of an individual response to allergens
* Regulation of isotype specificity, switch recombination regulation, and the mechanism of switching
* Two lymphocyte-specific proteins, RAG1 and RAG2, initiate V(D)J recombination of antigen receptor genes

General

Imprint:	Academic Press Inc
Country of origin:	United States
Series:	Advances in Immunology
Release date:	March 1996
First published:	February 1996
Volume editors:	Frank J. Dixon
Dimensions:	229 x 152 x 26mm (L x W x T)
Format:	Hardcover
Pages:	416
ISBN-13:	978-0-12-022461-6
Categories:	Books > Science & Mathematics > Biology, life sciences > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General
LSN:	0-12-022461-5
Barcode:	9780120224616

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