The lung receives the entire cardiac output from the right heart
and must load oxygen onto and unload carbon dioxide from perfusing
blood in the correct amounts to meet the metabolic needs of the
body. It does so through the process of passive diffusion.
Effective diffusion is accomplished by intricate parallel
structures of airways and blood vessels designed to bring
ventilation and perfusion together in an appropriate ratio in the
same place and at the same time. Gas exchange is determined by the
ventilation-perfusion ratio in each of the gas exchange units of
the lung. In the normal lung ventilation and perfusion are well
matched, and the ventilation-perfusion ratio is remarkably uniform
among lung units, such that the partial pressure of oxygen in the
blood leaving the pulmonary capillaries is less than 10 Torr lower
than that in the alveolar space. In disease, the disruption to
ventilation-perfusion matching and to diffusional transport may
result in inefficient gas exchange and arterial hypoxemia. This
volume covers the basics of pulmonary gas exchange, providing a
central understanding of the processes involved, the interactions
between the components upon which gas exchange depends, and basic
equations of the process. Table of Contents: Introduction / Anatomy
of the Gas Exchanger / Gas Carriage / Gas Exchange by Diffusion /
Gas Exchange and the Matching of Ventilation and Perfusion /
Evaluating Pulmonary Gas Exchange / Summary / References
General
Imprint: |
Morgan & Claypool Publishers
|
Country of origin: |
United States |
Series: |
Colloquium Series on Integrated Systems Physiology: From Molecule to Function |
Release date: |
August 2013 |
First published: |
August 2013 |
Authors: |
G.Kim Prisk
• Susan R. Hopkins
|
Dimensions: |
235 x 191 x 5mm (L x W x T) |
Format: |
Paperback
|
Pages: |
86 |
ISBN-13: |
978-1-61504-450-4 |
Categories: |
Books >
Medicine >
Pre-clinical medicine: basic sciences >
Physiology >
General
|
LSN: |
1-61504-450-7 |
Barcode: |
9781615044504 |
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