Fibrin Sealant in Operative Medicine - Volume 1: Otorhinolaryngology (Paperback, Softcover reprint of the original 1st ed. 1986)

Fibrin plays a prominent role in wound healing. It has a hemostatic effect, induces cellular response to wound damage,' and, by forming strands to build a matrix, assists in neovascularization and fibroblast proliferation. The concept of using clotting substances from human blood for wound manage- ment and to achieve hemostasis in bleeding parenchymatous organs can be traced to 1909, when Bergel [1] reported on the hemostatic effect of fibrin powder. In 1915, Grey [3] employed fibrin to control bleeding in neurosurgical operations of the brain. A year later, Harvey [4] used fibrin patches to stop bleeding from parenchy- matous organs in general surgery. It took more than two decades for this ingenious idea to be rediscovered. In 1940, Young and Medawar [8] reported on experimental nerve anastomosis by sealing. Similarly, Tarlov and Benjamin [7] reunited nerves with plasma clots in 1943. Tarlov improved the results obtained with clot anastomosing of nerves by avoiding tension at the nerve stumps. In 1944, Cronkite et al. [2] reported on an initial series of eight cases in which fibrinogen and thrombin had been used successfully for anchoring skin grafts.

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Release date:	August 1986
First published:	1986
Editors:	G. Schlag • H. Redl
Dimensions:	244 x 170 x 9mm (L x W x T)
Format:	Paperback
Pages:	163
Edition:	Softcover reprint of the original 1st ed. 1986
ISBN-13:	978-3-540-16734-1
Categories:	Books > Medicine > Surgery > General surgery Books > Medicine > Clinical & internal medicine > Otorhinolaryngology (ENT) > General
LSN:	3-540-16734-X
Barcode:	9783540167341

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