The idea that the microbial communities within the GI tract have a
profound influence on general human health actually originated with
Russian scientist Elie Metchnikov at the turn ofthe last century.
Also known as the "fatherofimmunol- ogy", Metchnikovbelievedthat
putrefactivebacteriain the gut were responsible for enhancing the
aging process. He theorized that ingestion ofhealthy bacteria found
in fermented foods could counteract toxic bacteria and was the key
to good health. His theories concerning good bacteria and health
can be found in his treatise "The ProlongationofLife: Optimistic
Studies".Thesewritings promptedJapanesescientist Minoru
Shirotatobegin investigationofhow fermentative bacteriaimprove
health. He succeededin isolating astrainofLactobacillusthat could
survive passage through the intestine, while promoting a healthy
balance ofmicrobes. The "Shirota strain" is still used today in the
fermented beverage Yakult.It is clear from a commercial standpoint
that these ideas have inspired the development of a probiotic
industry, which has expanded greatly in the U.S. over the past 5-10
years.
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