A large number of cardiovascular diseases are accompanied by
inflammation. This volume on the molecular basis of
microcirculatory disorders gives a comprehensive summary of key
steps in the inflammatory cascade. Leading investigators present a
state-of-the-art analysis of the molecular determinants of
leukocyte-endothelial cell adhesion, mechanotransduction in
endothelial and inflammatory cells, mechanisms of cell activation,
microvascular apoptosis with applications to ischemia-reperfusion
in the brain, the heart and in venous disease, diabetes and
hypertension. The book provides the latest thinking in these
important cardiovascular problems, with the most contemporary
literature and a look at the increasingly complex events during
inflammation. Molecular biology tools, microvascular and modern
bioengineering analysis are seamlessly integrated into the analysis
of clinical problems. The book helps not only newcomers to gain
entry into the interesting problems associated with microvascular
disorders, but lays the foundation for the design of new
therapeutic interventions.
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